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《医学前沿(英文)》 2014年 第8卷 第2期 页码 241-249 doi: 10.1007/s11684-014-0328-0
Approximately 70% of newly diagnosed bladder tumors are non-muscle invasive bladder cancer (NMIBC). NMIBC accounts for approximately 80% of total bladder cancer cases. Bacillus Calmette-Guérin (BCG) instillation and maintenance is considered as the standard adjuvant treatment for superficial bladder cancer. A number of randomized studies have focused on the benefit of maintenance therapy following initial BCG induction. To provide further insights into the effect of intravesical instillation on recurrence in patients with NMIBC, we analyzed this relationship by conducting an updated detailed meta-analysis. Evidence suggested that adjuvant intravesical BCG with maintenance treatment is significantly effective for the prophylaxis of tumor recurrence in patients with NMIBC.
关键词: non-muscle invasive bladder cancer bacillus Calmette-Guérin (BCG) meta-analysis
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《医学前沿(英文)》 2017年 第11卷 第4期 页码 528-535 doi: 10.1007/s11684-017-0573-0
The prevalence of tuberculosis infection among adolescents born after terminating the Bacillus Calmette–Guérin (BCG) booster vaccination in China was estimated using tuberculin skin testing (TST) and QuantiFERON-TB Gold assay (QFT) to investigate the influence of neonatal BCG vaccination on the performance of TST. Data analysis was conducted for 2831 eligible participants aged 5–15 years from the baseline survey of a population-based multi-center prospective study. The prevalence rates of TST (induration≥10 mm) and QFT positivity were 9.3% (264/2827) and 2.5% (71/2831), respectively. The rate of QFT indeterminate result was 2.2% (62/2831). The overall agreement between TST and QFT was low (concordance= 88.0%; κ coefficient= 0.125). Only TST was positively associated with BCG vaccination with an adjusted odds ratio of 1.71 [95% confidence interval, 1.26–2.31]. A history of close contact with patients of active TB was significantly associated with positivity for TST and QFT. Our results suggested that BCG neonatal vaccination still affects TST performance, and a two-step approach might be considered for TB infection testing among adolescents in China.
关键词: tuberculin skin test interferon-γ release assays adolescent agreement
PAN Jiangang, ZHOU Xing, CHEN Zhiguang, HAN Ruifa
《医学前沿(英文)》 2008年 第2卷 第3期 页码 259-263 doi: 10.1007/s11684-008-0049-3
FAN Xiaodong, HAN Ruifa
《医学前沿(英文)》 2007年 第1卷 第4期 页码 377-380 doi: 10.1007/s11684-007-0073-8
Telomeric impact of conventional chemotherapy
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《医学前沿(英文)》 2013年 第7卷 第4期 页码 411-417 doi: 10.1007/s11684-013-0293-z
The increased level of chromosome instability in cancer cells, leading to aneuploidy and gross chromosomal rearrangements, is not only a driving force for oncogenesis but also can be the Achille’s heel of the disease since many chemotherapies (CT) kill cells by inducing a non-tolerable rate of DNA damage. A wealth of published evidence showed that telomere stability can be more affected than the bulk of the genome by several conventional antineoplasic drugs. These results raise the interesting possibility that CT with genotoxic drugs preferentially target telomeres. In agreement with this view, accelerated shortening of telomere length has been described in blood lineage cells following high-dose CT (stem cell transplantation) or non-myeloablative CT. However, almost nothing is known on the consequences of this shortening in terms of telomere stability, senescence and on the development of second cancers or post-treatment aging-like syndromes in cancer survivors (cognitive defect, fertility impairment, etc.). In this article, we propose: (1) telomeres of cancer cells are preferential genomic targets of chemotherapies altering chromosome maintenance; (2) telomere functional parameters can be a surrogate marker of chemotherapy sensitivity and toxicity; (3) the use of anti-telomere molecule could greatly enhance the sensitivity to standards chemotherapies.
关键词: telomere antineoplasic drugs conventional chemotherapies
Characterization of Bacillus amyloliquefacien contaminating 75% alcohol disinfectant
ZHANG Wanming, YUAN Yuesha, BIAN Cangli, TU Xianyu, ZHANG Wen, HUANG Huqiang, WANG Lan
《医学前沿(英文)》 2008年 第2卷 第1期 页码 113-116 doi: 10.1007/s11684-008-0021-2
Use of dry yeast cells as a cheap nitrogen source for lactic acid production by thermophilic
Kim Yng Ooi, Jin Chuan Wu
《化学科学与工程前沿(英文)》 2015年 第9卷 第3期 页码 381-385 doi: 10.1007/s11705-015-1534-2
关键词: L-lactic acid thermophilic strain Bacillus coagulans dry yeast cells autolysis fermentation
《环境科学与工程前沿(英文)》 2023年 第17卷 第1期 doi: 10.1007/s11783-023-1609-0
● Improved Cr phytoextration efficiency was achieved by B. cereus inoculation.
关键词: Hexavalent chromium Hyperaccumulator Rhizobacteria Leersia hexandra Swartz Bacillus cereus Consortia
解淀粉芽孢杆菌发酵红小豆的理化特性和生物活性 Article
吴珊, 卢帅, 刘军, 杨绍青, 闫巧娟, 江正强
《工程(英文)》 2021年 第7卷 第2期 页码 219-225 doi: 10.1016/j.eng.2020.10.010
本研究采用解淀粉芽孢杆菌发酵红小豆(Vigna umbellata),并评价了发酵红小豆的理化特性和生物活性。以纤溶酶活性为指标优化了发酵条件,在最适发酵条件下,纤溶酶活性最高达78.0 FU∙g-1(4890 IU∙g-1,纤维蛋白平板法)。发酵红小豆中多肽含量(2.1~10.9 g∙100 g-1)、总酚含量(116.7~388.5 mg没食子酸∙100 g-1)、总黄酮含量(235.5~354.3 mg芦丁∙100 g-1)、花青素含量(20.1~47.1 mg∙100 g-1)和超氧化物歧化酶活性(55.3~263.6 U∙g-1)显著增加。红小豆经发酵后的2,2-二苯基-1-苦肼基(DPPH)和2,2-联氮双(3-乙基苯并噻唑啉-6-磺酸)二铵盐(ABTS)自由基清除活性和铁离子还原抗氧化能力(FRAP)较未发酵的红小豆提高1.9~4.8倍。此外,发酵红小豆的二肽基肽酶Ⅳ(DPP-Ⅳ)抑制活性、α-葡萄糖苷酶抑制活性和抗凝血活性显著提高。解淀粉芽孢杆菌发酵红小豆具有多种功能活性,对开发预防血栓性疾病的功能食品具有重要意义。
Roles of acid-producing bacteria in anaerobic digestion of waste activated sludge
Sijia Ai, Hongyu Liu, Mengjie Wu, Guangming Zeng, Chunping Yang
《环境科学与工程前沿(英文)》 2018年 第12卷 第6期 doi: 10.1007/s11783-018-1050-y
Three acid-producing strains were isolated and identified. The isolated bacteria accelerated the anaerobic digestion processes. Bacillus coagulans improved TCOD removal, VS removal and biogas production. The optimal inoculum concentration of Bacillus coagulans AFB-1 was 30%.
关键词: Anaerobic digestion Waste activated sludge Acid-producing bacteria Bacillus coagulans
Yanli LIU, Rong LIU, Cheng ZHEN, Quanfang GUO, Liping WU, Zhaoxi DING, Yushun BI, Zhiyu LIU
《医学前沿(英文)》 2009年 第3卷 第1期 页码 91-95 doi: 10.1007/s11684-009-0011-z
关键词: Fuganling granula immunological liver injury bacille calmette guerin lipopolysaccharide mice
Effect of calcium lactate on compressive strength and self-healing of cracks in microbial concrete
Kunamineni VIJAY, Meena MURMU
《结构与土木工程前沿(英文)》 2019年 第13卷 第3期 页码 515-525 doi: 10.1007/s11709-018-0494-2
关键词: calcium lactate bacillus subtilis compressive strength self-healing of cracks
Climate change and China’s mega urban regions
Chaolin GU, Sunsheng HAN
《结构与土木工程前沿(英文)》 2010年 第4卷 第4期 页码 418-430 doi: 10.1007/s11709-010-0075-5
Energy internet technology: modeling, optimization and dispatch of integrated energy systems
Shilie WENG, Chenghong GU, Yiwu WENG
《能源前沿(英文)》 2018年 第12卷 第4期 页码 481-483 doi: 10.1007/s11708-018-0604-9
Reconfigurable manufacturing systems: Principles, design, and future trends
Yoram KOREN, Xi GU, Weihong GUO
《机械工程前沿(英文)》 2018年 第13卷 第2期 页码 121-136 doi: 10.1007/s11465-018-0483-0
Reconfigurable manufacturing systems (RMSs), which possess the advantages of both dedicated serial lines and flexible manufacturing systems, were introduced in the mid-1990s to address the challenges initiated by globalization. The principal goal of an RMS is to enhance the responsiveness of manufacturing systems to unforeseen changes in product demand. RMSs are cost-effective because they boost productivity, and increase the lifetime of the manufacturing system. Because of the many streams in which a product may be produced on an RMS, maintaining product precision in an RMS is a challenge. But the experience with RMS in the last 20 years indicates that product quality can be definitely maintained by inserting in-line inspection stations. In this paper, we formulate the design and operational principles for RMSs, and provide a state-of-the-art review of the design and operations methodologies of RMSs according to these principles. Finally, we propose future research directions, and deliberate on how recent intelligent manufacturing technologies may advance the design and operations of RMSs.
关键词: reconfigurable manufacturing systems responsiveness intelligent manufacturing
标题 作者 时间 类型 操作
Can intravesical bacillus Calmette-Guérin reduce recurrence in patients with non-muscle invasive bladder
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期刊论文
Testing of tuberculosis infection among Chinese adolescents born after terminating the Bacillus Calmette--Guérin booster vaccination: subgroup analysis of a population-based cross-sectional study
null
期刊论文
A meta-analysis of randomized trials of maintenance bacillus Calmette-Guerin instillation efficacy against
PAN Jiangang, ZHOU Xing, CHEN Zhiguang, HAN Ruifa
期刊论文
Study of recombinant human IFN-α-2b bacilli Calmette–Guerin activated killer cells and against bladder
FAN Xiaodong, HAN Ruifa
期刊论文
Characterization of Bacillus amyloliquefacien contaminating 75% alcohol disinfectant
ZHANG Wanming, YUAN Yuesha, BIAN Cangli, TU Xianyu, ZHANG Wen, HUANG Huqiang, WANG Lan
期刊论文
Use of dry yeast cells as a cheap nitrogen source for lactic acid production by thermophilic
Kim Yng Ooi, Jin Chuan Wu
期刊论文
Chromium phytoextraction and physiological responses of the hyperaccumulator Swartz to plant growth-promoting rhizobacterium inoculation
期刊论文
Roles of acid-producing bacteria in anaerobic digestion of waste activated sludge
Sijia Ai, Hongyu Liu, Mengjie Wu, Guangming Zeng, Chunping Yang
期刊论文
Experimental study on the efficacy of Fuganling granula on protecting against immunological hepatic injury
Yanli LIU, Rong LIU, Cheng ZHEN, Quanfang GUO, Liping WU, Zhaoxi DING, Yushun BI, Zhiyu LIU
期刊论文
Effect of calcium lactate on compressive strength and self-healing of cracks in microbial concrete
Kunamineni VIJAY, Meena MURMU
期刊论文
Energy internet technology: modeling, optimization and dispatch of integrated energy systems
Shilie WENG, Chenghong GU, Yiwu WENG
期刊论文